The compressibility at room temperature and the thermal expansion at room pressure of two disordered crystals (space group C2/c) obtained by annealing a natural omphacite sample (space group P2/n) of composition close to Jd 56Di 44 and Jd 55Di 45, respectively, have been studied by single-crystal X-ray diffraction. Using a Birch-Murnaghan equation of state truncated at the third order [BM3-EoS], we have obtained the following coefficients: V 0 = 421.04(7) Å 3, K T0 = 119(2) GPa, K′ = 5.7(6). A parameterized form of the BM3 EoS was used to determine the axial moduli of a, b and c. The anisotropy scheme is β c ≤ β a ≤ β b, with an anisotropy ratio 1.05:1.00:1.07. A fitting of the lattice variation as a function of temperature, allowing for linear dependency of the thermal expansion coefficient on the temperature, yielded α V(1bar,303K) = 2.64(2) × 10 -5 K -1 and an axial thermal expansion anisotropy of α b ≫ α a > α c. Comparison of our results with available data on compressibility and thermal expansion shows that while a reasonable ideal behaviour can be proposed for the compressibility of clinopyroxenes in the jadeite-diopside binary join [K T0 as a function of Jd molar %: K T0 = 106(1) GPa + 0.28(2) × Jd (mol%)], the available data have not sufficient quality to extract the behaviour of thermal expansion for the same binary join in terms of composition.