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American Society for Microbiology, Journal of Clinical Microbiology, 7(49), p. 2711-2713, 2011

DOI: 10.1128/jcm.00864-11

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Method for phenotypic detection of extended-spectrum beta-lactamases in enterobacter species in the routine clinical setting

Journal article published in 2011 by James Cohen Stuart, Maurine Leverstein van Hall, Bram Diederen, Nashwan al Naiemi, N. Al Naiemi, Nashwan Al Naiemi, Ad Fluit, Niek Arents, Steven Thijsen, Bart Vlaminckx, Johan W. Mouton ORCID, Maurine Leverstein-Van Hall
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT In 271 Enterobacter blood culture isolates from 12 hospitals, extended-spectrum beta-lactamase (ESBL) prevalence varied between 0% and 30% per hospital. High prevalence was associated with dissemination, indicating the potential relevance of infection control measures. Screening with cefepime or Vitek 2, followed by a cefepime/cefepime-clavulanate Etest, was an accurate strategy for ESBL detection in Enterobacter isolates (positive predictive value, 100%; negative predictive value, 99%).