Published in
American Society for Microbiology, Journal of Bacteriology, 3(192), p. 888-892, 2010
DOI: 10.1128/jb.01255-09
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Genome Sequence of a Recently Emerged, Highly Transmissible, Multi-Antibiotic- and Antiseptic-Resistant Variant of Methicillin-Resistant Staphylococcus aureus, Sequence Type 239 (TW)
Journal article published in 2009 by
Matthew T. G. Holden,
Jodi A. Lindsay,
Craig Corton,
Michael A. Quail,
Joshua D. Cockfield,
Smriti Pathak,
Rahul Batra,
Julian Parkhill 
,
Stephen D. Bentley,
Jonathan D. Edgeworth
,
Stephen D. Bentley,
Jonathan D. Edgeworth
This paper is made freely available by the publisher.
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Abstract
ABSTRACT The 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions (635 kb and 127 kb). The strain is resistant to a wide range of antibiotics, antiseptics, and heavy metals due to resistance genes encoded on mobile genetic elements and also mutations in housekeeping genes.