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American Society for Microbiology, Journal of Bacteriology, 3(192), p. 896-900, 2010

DOI: 10.1128/jb.01122-09

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Characterization of the CtsR stress response regulon in Lactobacillus plantarum

Journal article published in 2009 by Daniela Fiocco, Vittorio Capozzi, Michael Collins, Anna Gallone, Pascal Hols, Jean Guzzo, Stephanie Weidmann, Aurélie Rieu ORCID, T. Msadek And G. Spano, Giuseppe Spano
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Lactobacillus plantarum ctsR was characterized. ctsR was found to be cotranscribed with clpC and induced in response to various abiotic stresses. ctsR deletion conferred a heat-sensitive phenotype with peculiar cell morphological features. The transcriptional pattern of putative CtsR regulon genes was examined in the Δ ctsR mutant. Direct CtsR-dependent regulation was demonstrated by DNA-binding assays using recombinant CtsR and the promoters of the ctsR - clpC operon and hsp1 .