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Springer Verlag, International Journal of Clinical and Laboratory Research, 1-4(23), p. 225-227

DOI: 10.1007/bf02592314

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Cytokeratins patterns in childhood primary liver tumors

Journal article published in 1993 by P. Pontisso ORCID, M. Barzon, G. Basso, G. Cecchetto, G. Perilongo, A. Alberti
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

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Preprint: archiving allowed
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Data provided by SHERPA/RoMEO

Abstract

Expression of cytokeratins no. 7 and no. 19, typical of the mature biliary tract and of embryonic and fetal hepatocytes, has been evaluated in primary liver tumors from 12 children. Of 7 children with hepatoblastoma, 6 were strongly reactive for cytokeratin no. 19 and only 4 were weakly positive for cytokeratin no. 7. In contrast, the remaining tumors, including 2 hepatocarcinomas, 1 sarcoma, 1 hamartoma and 1 hemangioma were positive for cytokeratin no. 7, while cytokeratin 19 was present in 1 hepatocarcinoma and in the hamartoma. All these tumors, as well as 1 hepatoblastoma and the sarcoma, were also reactive for cytokeratin no. 8, typical of hepatic cells.