Published in
American Chemical Society, Journal of Organic Chemistry, 16(74), p. 6169-6180
DOI: 10.1021/jo901073v
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Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds
Journal article published in 2009 by
John R. Goodell,
Jonathan P. McMullen,
Nikolay Zaborenko,
Jason R. Maloney,
Chuan-Xing Ho,
Klavs F. Jensen 
,
John A. Porco,
Aaron B. Beeler
,
John A. Porco,
Aaron B. Beeler
This paper is available in a repository.
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Abstract
An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo[3.2.1]octanoid scaffolds will be described.