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Cold Spring Harbor Laboratory Press, Genes & Development, 9(28), p. 923-925, 2014

DOI: 10.1101/gad.242735.114

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LINking microRNAs, kidney development, and Wilms tumors

Journal article published in 2014 by Peter Hohenstein ORCID, Nicholas D. Hastie
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

In this issue of Genes & Development, Urbach and colleagues (pp. 971–982) provide compelling data suggesting a role for LIN28 in the pathogenesis of a significant percentage of Wilms tumors. These data extend our insights in the genetics underlying Wilms tumor development and emphasize the importance of stemness and microRNA-mediated processes in the origins of these tumors.