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American Society for Microbiology, Journal of Bacteriology, 13(185), p. 3972-3977, 2003

DOI: 10.1128/jb.185.13.3972-3977.2003

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The dinB Operon and Spontaneous Mutation in Escherichia coli

Journal article published in 2003 by Gregory J. McKenzie, Daniel B. Magner, Peter L. Lee, Susan M. Rosenberg ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Apparently conflicting data regarding the role of SOS-inducible, error-prone DNA polymerase IV (DinB) in spontaneous mutation are resolved by the finding that mutation is reduced by a polar allele with which dinB and neighboring yafN are deleted but not by two nonpolar dinB alleles. We demonstrate the existence of a dinB operon that contains four genes, dinB - yafN - yafO - yafP . The results imply a role for yafN , yafO , and/or yafP in spontaneous mutation.