Purpose(Introduction) : Online database offers an easy access to evidence,based information and facilitates the integration of evidence into practice by providing summarized recommendations for clinical services. Objectives:This study aims to understand the motives of health professionals in the use of online database.Methods : A constructed questionnaire survey was carried out to examine the correlation of accessing online evidence retrieval systems with the motivation among 2975 nationwide representatives in the regional teaching hospitals of Taiwan. Statistical analysis was performed by chi square test using commercial available software.Results : The most common motivation to access the online database was class assignment (62.2%), followed by searching information for clinical practice (56.1%), instruction preparation (37.8%), personal interest (28.3%), and research (22.4%). Specifically, physicians used online databases to locate health information the most for clinical practice (76.6%), followed by instruction preparation (63.3%), and research (57.0%). Nevertheless, nurses used such databases more often for class assignments (66.4%) and clinical practice (55.8%). In addition, the motives among health professionals who accessed the Cochrane Library were associated with searching information for clinical practice, class assignment, instruction preparation, personal interest, research need, and medical accreditation (P