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Elsevier, Tetrahedron Letters, 47(51), p. 6111-6115

DOI: 10.1016/j.tetlet.2010.09.047

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A synthetic ditryptophan conjugate that rescues bacteria from mercury toxicity through complexation

Journal article published in 2010 by Sudipta Mondal ORCID, Shiv Swaroop, Ramanathan Gurunath, Sandeep Verma
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

The synthesis of ditryptophan-pyridine conjugates and their binding to mercury ions is described. Conjugate 3 shows an excellent ability to sequester mercury from solution and rescue bacterial growth in a concentration-dependent survival assay. It is proposed that such compounds, composed primarily of bioessential/biodegradable components, could be potentially used as sequestrating agents for the removal of Hg(II) ions in detoxification strategies.