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Oxford University Press, Nucleic Acids Research, D1(44), p. D481-D487, 2015

DOI: 10.1093/nar/gkv1351

Oxford University Press, Nucleic Acids Research, D1(42), p. D472-D477, 2013

DOI: 10.1093/nar/gkt1102

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The Reactome pathway Knowledgebase

Journal article published in 2015 by David Croft, Antonio Fabregat, Antonio Fabregat Mundo, Konstantinos Sidiropoulos ORCID, Phani Garapati, Kerstin Hausmann, Robin Haw, Marc Gillespie, Michael Caudy, Bijay Jassal, Florian Korninger, Marija Milacic, Steven Jupe, Maulik R. Kamdar, Sheldon McKay and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Reactome (http://www.reactome.org) is a manually curated open-source open-data resource of human pathways and reactions. The current version 46 describes 7088 human proteins (34% of the predicted human proteome), participating in 6744 reactions based on data extracted from 15 107 research publications with PubMed links. The Reactome Web site and analysis tool set have been completely redesigned to increase speed, flexibility and user friendliness. The data model has been extended to support annotation of disease processes due to infectious agents and to mutation.