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Elsevier, The Lancet Neurology, 9(12), p. 873-881

DOI: 10.1016/s1474-4422(13)70146-7

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MRI investigation of the sensorimotor cortex and the corticospinal tract after acute spinal cord injury: a prospective longitudinal study

Journal article published in 2013 by Patrick Freund, Nikolaus Weiskopf, John Ashburner ORCID, Katharina Wolf, Reto Sutter, Daniel R. Altmann, Karl Friston, Alan Thompson, Armin Curt
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

In patients with chronic spinal cord injury, imaging of the spinal cord and brain above the level of the lesion provides evidence of neural degeneration; however, the spatial and temporal patterns of progression and their relation to clinical outcomes are uncertain. New interventions targeting acute spinal cord injury have entered clinical trials but neuroimaging outcomes as responsive markers of treatment have yet to be established. We aimed to use MRI to assess neuronal degeneration above the level of the lesion after acute spinal cord injury.