High precision measurements of the Cosmic Microwave Background (CMB) represent one of the most difficult challenges in observational cosmology, but promise to unveil the mysteries of the very early Universe and of the birth of structures. Three observables are available. The small polarized CMB signal is probably carrying a signature of the early inflationary dynamics of the Universe. It is, however, embedded in overwhelming noise, systematic effects, and polarized foreground. The imprint of the large scale structure in the universe is present in the small-scale anisotropy of the CMB and in its spectral signatures (secondary anisotropy), again mixed with foreground contaminants. Low-level non-Gaussian components of CMB anisotropy and polarization also provide a very promising way to constrain inflation and the physics of ultra-high energies, if foregrounds can be efficiently separated from the measured signal. If measured with high precision, as required by the science issues above, the spectra of CMB anisotropy and polarization also constrain efficiently neutrino properties, hence their interest in this conference. Here we summarize the current status of CMB measurements, dominated by the Planck survey, and delineate the forthcoming activities, needed to exploit the huge scientific potential of precision measurements of the CMB, including the detection of neutrino masses. © 2011 Elsevier B.V.