Dissemin is shutting down on January 1st, 2025

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Wiley, British Journal of Pharmacology, 5(137), p. 710-718, 2002

DOI: 10.1038/sj.bjp.0704922

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Inotropic responses to human gene 2 (B29) relaxin in a rat model of myocardial infarction (MI): effect of pertussis toxin

Journal article published in 2002 by Andrew R. Kompa ORCID, Chrishan S. Samuel, Roger J. Summers ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Relaxin produces powerful inotropic and chronotropic responses in isolated atria. The effect of relaxin has been examined in a rat model of cardiac failure, induced by myocardial infarction (MI).Maximum inotropic responses to isoprenaline (sham 5.4±0.3 mN; MI 2.6±0.3 mN; P