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Wiley, British Journal of Pharmacology, 2(134), p. 434-440, 2001

DOI: 10.1038/sj.bjp.0704235

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Apocynin and 1400 W prevents airway hyperresponsiveness during allergic reactions in mice

Journal article published in 2001 by Richard B. R. Muijsers, Ingrid van Ark, Gert Folkerts, Andries S. Koster ORCID, Antoon J. M. van Oosterhout, Dirkje S. Postma, Frans P. Nijkamp
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The contribution of reactive nitrogen species to the development of airway hyperresponsiveness in a mouse model of allergic inflammation was investigated by the use of selective inhibitors of nitric oxide and superoxide formation.Sensitized mice, repeatedly challenged with ovalbumin showed a significant (P