Published in
Oxford University Press, Clinical Infectious Diseases, 2(55), p. 291-300, 2012
DOI: 10.1093/cid/cis383
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- ORCID
- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Effects of Recombinant Human Interleukin 7 on T-Cell Recovery and Thymic Output in HIV-Infected Patients Receiving Antiretroviral Therapy: Results of a Phase I/IIa Randomized, Placebo-Controlled, Multicenter Study
Journal article published in 2012 by
Y. Lévy,
I. Sereti,
G. Tambussi,
J. P. Routy,
J. D. Lelièvre 
,
J. F. Delfraissy,
J. M. Molina,
M. Fischl,
C. Goujard,
B. Rodriguez,
C. Rouzioux,
V. Avettand-Fenoël,
T. Croughs,
S. Beq,
M. Morre
and other authors.
,
J. F. Delfraissy,
J. M. Molina,
M. Fischl,
C. Goujard,
B. Rodriguez,
C. Rouzioux,
V. Avettand-Fenoël,
T. Croughs,
S. Beq,
M. Morre
and other authors.
This paper is available in a repository.
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Abstract
Interleukin 7 induces a well-tolerated, dose-dependent, and sustained increase of CD4 T cells in human immunodeficiency virus-infected individuals treated with antiretroviral therapy, through an expansion of peripheral T cells that do not express activation markers, and increases thymic output in some patients.