This study examined the Beck Depression Inventory-II (BDI-II) with Confirmatory Factor Analysis and followed up cardiac morbidity and mortality for a median of 4.9 years among 226 coronary artery bypass graft patients. Cardiac morbidity and mortality events (n = 65, 28.8%) were associated with BDI-II cognitive factor z-score (adjusted hazard ratio = 1.36, 95% confidence interval 1.02 — 1.82, p = .04), controlling for left ventricular impairment, age, respiratory disease, heart failure, renal disease and diabetes. A cognitive depression factor marked by pessimism, past failure, self-criticalness and worthlessness was consistently associated with cardiac morbidity and mortality, contrasting to other work. ; Phillip J. Tully, Helen R. Winefield, Robert A. Baker, Deborah A. Turnbull, Peter de Jonge