Elsevier, The Lancet Oncology, 1(13), p. e11-e22, 2012
DOI: 10.1016/s1470-2045(11)70175-9
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Although liver transplantation is a widely accepted treatment for hepatocellular carcinoma (HCC), much controversy remains and there is no generally accepted set of guidelines. An international consensus conference was held on Dec 2–4, 2010, in Zurich, Switzerland, with the aim of reviewing current practice regarding liver transplantation in patients with HCC and to develop internationally accepted statements and guidelines. The format of the conference was based on the Danish model. 19 working groups of experts prepared evidence-based reviews according to the Oxford classifi cation, and drafted recommendations answering 19 specifi c questions. An independent jury of nine members was appointed to review these submissions and make fi nal recommendations, after debates with the experts and audience at the conference. This report presents the fi nal 37 statements and recommendations, covering assess ment of candidates for liver transplantation, criteria for listing in cirrhotic and non-cirrhotic patients, role of tumour downstaging, management of patients on the waiting list, role of living donation, and post-transplant management.