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Wiley, Hepatology, 2(63), p. 566-573, 2015

DOI: 10.1002/hep.28148

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Thrombelastography-guided blood product use before invasive procedures in cirrhosis with severe coagulopathy: A randomized, controlled trial

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Bleeding is a feared complication of invasive procedures in patients with cirrhosis and significant coagulopathy (as defined by routine coagulation tests), and is used to justify pre-procedure use of fresh frozen plasma (FFP) and/or platelets (PLT). Thromboelastography (TEG) provides a more comprehensive global coagulation assessment than routine tests (INR and platelet count) and its use may avoid unnecessary blood product transfusion in patients with cirrhosis and significant coagulopathy (defined in this study as INR>1.8 and/or platelet count 40mm and/or PLT if maximum amplitude (MA) 1.8 and/or platelet count 40 min and/or PLT if maximum amplitude (MA) was