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Elsevier, Bioorganic and Medicinal Chemistry Letters, 24(18), p. 6374-6376

DOI: 10.1016/j.bmcl.2008.10.086

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α-S-GalCer: Synthesis and Evaluation for iNKT Cell Stimulation

Journal article published in 2008 by Marisa L. Blauvelt, S. Brian Wilson, Maryam Khalili, Weonjoo Jaung, Janet Paulsen, Amy C. Anderson, S. Brian Wilson, Amy R. Howell ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The synthesis and evaluation for iNKT stimulation of alpha-S-galactosylceramide is reported. Prepared by alkylation of a galactosylthiol, this analog of the potent immunostimulatory agent, KRN7000, did not stimulate iNKT cells either in vitro or in vivo.