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American Society of Hematology, Blood, 18(124), p. 2858-2866, 2014

DOI: 10.1182/blood-2014-03-563445

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Splenic TFH expansion participates in B-cell differentiation and antiplatelet-antibody production during immune thrombocytopenia

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points Human splenic TFH expansion during ITP participates in B-cell differentiation and antiplatelet-antibody production. IL-21 and CD40 are key TFH molecules that could be promising targets in the treatment of ITP.