Published in
American Society of Hematology, Blood, 25(123), p. 3914-3924, 2014
DOI: 10.1182/blood-2012-12-473439
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A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis
Journal article published in 2014 by
Tobias Berg,
Silvia Thoene,
Damian Yap 
,
Tracee Wee,
Nathalie Schoeler,
Patty Rosten,
Emilia Lim,
Misha Bilenky,
Andrew J. Mungall ,
Thomas Oellerich,
Sherry Lee,
Courteney K. Lai,
Patricia Umlandt,
Anisa Salmi,
Harry Chang
and other authors.
,
Tracee Wee,
Nathalie Schoeler,
Patty Rosten,
Emilia Lim,
Misha Bilenky,
Andrew J. Mungall ,
Thomas Oellerich,
Sherry Lee,
Courteney K. Lai,
Patricia Umlandt,
Anisa Salmi,
Harry Chang
and other authors.
This paper is made freely available by the publisher.
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Abstract
Key Points A functional demonstration of the oncogenic role of mutated EZH2 in a mouse model is presented. The global effects of mutated EZH2 on expression and epigenome have been characterized.