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Oxford University Press (OUP), The Journal of Infectious Diseases, 4(205), p. 631-634

DOI: 10.1093/infdis/jir803

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Validation of Self-swab for Virologic Confirmation of Influenza Virus Infections in a Community Setting

Journal article published in 2011 by Dennis K. M. Ip, Martin Schutten, Vicky J. Fang, Rita O. P. Fung, Regina T. Dutkowski, Kwok-Hung Chan, Gabriel M. Leung, J. S. Malik Peiris, Benjamin J. Cowling ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Few studies have investigated the validity of self-collected nose and throat swabs for influenza confirmation in community settings. We followed outpatients with confirmed influenza with sequential measurement of viral loads and applied log-linear regression models to the viral shedding patterns. Among 176 outpatients with confirmed influenza, the detection of virus and quantitative viral loads obtained from self-swabs was consistent with statistical predictions based on earlier and later measurements, suggesting that self-collected nose and throat swabs can be a valid alternative for virologic confirmation of influenza A or B infection in a community setting.