The aim of this study was to gather methodological clues in the scope of a fractal description of non-planar surfaces, which clues can be used for testing biomaterials. The fundamentals of a few most popular fractal methods of surface analysis are discussed here and two new methods are proposed by presenting their basic assumptions. On this basis, appropriate programs for numerical calculations have been developed, while simultaneously using measuring files from instruments which enable stereometric measurement of surfaces (profilographometers, confocal microscopes, etc.).