Public Library of Science, PLoS ONE, 8(7), p. e42692, 2012
DOI: 10.1371/journal.pone.0042692
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Glycosaminoglycans (GAGs) are essential molecules that regulate diverse biological processes including cell adhesion, differentiation, signaling and growth, by interaction with a wide variety of proteins. However, despite the efforts committed to understand the molecular nature of the interactions in protein-GAG complexes, the answer to this question remains elusive.