A SPE-GC-FID method was developed for the analyzing the residues of prometryne and acetochlor in soil-water system. The sample solution was made up of the standard stock solution of prometryne-acetochlor and soil-water solution with a certain proportion.purified by C₁₈solid-phase extraction (SPE) column, and then leached by acetone. The leached was filtrated with microporous membrane (d<0.45 μm). The results showed that the standard curve was showed in the range of 1.5~30 μg/mL with a correlation coefficient of 0.9995 and 0.9980. The recoveries (n=5) were 98.9%~107.2%, with relative standard deviation ranged from 2.52% to 9.7%.The detection limits of prometryne was 0.22 μg/mL and acetochlor was 0.19 μg/mL. This method provides a dependable approach to examine and evaluate the residues of prometryne and acetochlor in the soil-water system.