MoS₂with rose-like morphology have been successfully synthesized using by an ionic liquid-directed hydrothermal synthesis. XRD results showed that the as-prepared MoS₂directed by ionic liquid Brij56 have the good peaks. SEM images revealed that the MoS₂nanoflowers had rose-like morphology composed of many stacked sheets. TEM images showed that MoS₂nanoflowers have incompactly petal-like stacked structure. These results showed that ionic liquid Brij56 could effectively influence the morphology of MoS₂. Ionic liquid played a crucial role as a structure-directed reagent in the formation of MoS₂nanoflowers and the possible growth mechanism of MoS₂nanoflowers was also discussed.