Composites of nanocellulose with layered silicates have recently emerged as a new type of composite materials offering superior strength, as well as thermal and gas barrier properties. These organic-inorganic hybrid composites with a nacre-like structure can be obtained from renewable resources and are environmentally friendly. They can potentially be presented as a serious alternative in the near future to several polymers or other polymer-inorganic composites, for applications in food packaging or electronic devices. The discussion here will be directed to: what are the new opportunities and challenges that arise for these materials aiming at their competition with well-established materials in the market.