Published in
American Society of Hematology, Blood, 24(125), p. 3720-3730, 2015
DOI: 10.1182/blood-2014-10-603951
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Altered lymphopoiesis and immunodeficiency in miR-142 null mice
Journal article published in 2015 by
Nicholas J. Kramer,
Wei-Le Wang 
,
Estefany Y. Reyes,
Bijender Kumar,
Ching-Cheng Chen,
Chandran Ramakrishna,
Edouard M. Cantin,
Steven L. Vonderfecht,
Konstantin D. Taganov,
Nelson Chau,
Mark P. Boldin
,
Estefany Y. Reyes,
Bijender Kumar,
Ching-Cheng Chen,
Chandran Ramakrishna,
Edouard M. Cantin,
Steven L. Vonderfecht,
Konstantin D. Taganov,
Nelson Chau,
Mark P. Boldin
This paper is made freely available by the publisher.
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Abstract
Key Points miR-142 is an essential regulator of lymphocyte ontogenesis and is required for the generation of humoral and cellular immunity in mice. miR-142-3p regulates B-cell homeostasis by controlling expression of BAFF-R.