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Centers for Disease Control and Prevention, Emerging Infectious Diseases, 11(8), p. 1347-1349, 2002

DOI: 10.3201/eid0811.020125

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Global Distribution of Mycobacterium tuberculosis Spoligotypes

Journal article published in 2002 by Ingrid Filliol, Jeffrey R. Driscoll, Dick van Soolingen, D. Van Soolingen, Barry N. Kreiswirth, Kristin Kremer, Georges Valétudie, Dang Duc Anh, Rachael Barlow, Dilip Banerjee, Pablo J. Bifani, Karin Brudey, Angel Cataldi, Robert C. Cooksey, Debby V. Cousins and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We present a short summary of recent observations on the global distribution of the major clades of the Mycobacterium tuberculosis complex, the causative agent of tuberculosis. This global distribution was defined by data-mining of an international spoligotyping database, SpolDB3. This database contains 11,708 patterns from as many clinical isolates originating from more than 90 countries. The 11,708 spoligotypes were clustered into 813 shared types. A total of 1,300 orphan patterns (clinical isolates showing a unique spoligotype) were also detected.