Published in

American Association for the Advancement of Science, Science, 6251(349), p. 956-960, 2015

DOI: 10.1126/science.aac9582

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Production of amorphous nanoparticles by supersonic spray-drying with a microfluidic nebulator

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Crystal nuclei beaten to the punch Amorphous nanoparticles often dissolve more rapidly than their crystalline counterparts, which can be useful in applications such as drug delivery. Amstad et al. made amorphous nanoparticles from organic and inorganic compounds—even table salt—using droplets of dissolved compounds created with a microfluidic nebulator. The solvent evaporates fast enough that nanoparticles form before crystal nuclei can develop. The small particle size inhibits crystallization for periods of months Science , this issue p. 956