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Mary Ann Liebert, Tissue Engineering Part B: Reviews, 21-22(21), p. 2703-2713

DOI: 10.1089/ten.tea.2015.0183

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Ligament Tissue Engineering Using a Novel Porous Polycaprolactone Fumarate Scaffold and Adipose Tissue-Derived Mesenchymal Stem Cells Grown in Platelet Lysate

Journal article published in 2015 by Eric R. Wagner, Dalibel Bravo, Mahrokh Dadsetan, Scott M. Riester, Steven Chase, Jennifer J. Westendorf, Allan B. Dietz ORCID, Andre J. van Wijnen, Michael J. Yaszemski, Sanjeev Kakar
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Purpose: Surgical reconstruction of intra-articular ligament injuries is hampered by the poor regenerative potential of the tissue. We hypothesized that a novel composite polymer “neoligament” seeded with progenitor cells and growth factors would be effective in regenerating native ligamentous tissue.