Mathematical Modeling of the Release of Active Ingredients from a Contraceptive Patch: Ortho Evra® as a Case Study

Trujillo-De Santiago, Grissel; Patricio Sáenz-Collins, Carlos; Álvarez, Mario Moisés; García-Arellano, Lizette; ?lvarez, M. M.; Moisés Álvarez, Mario

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Mathematical Modeling of the Release of Active Ingredients from a Contraceptive Patch: Ortho Evra® as a Case Study

Journal article published in 2014 by Grissel Trujillo-De Santiago

, Carlos Patricio Sáenz-Collins, Mario Moisés Álvarez, Lizette García-Arellano, M. M. ?lvarez, Mario Moisés Álvarez

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Abstract

Contraceptive patches have become a frequently used contraceptive method. We present a mathematical model that describes the serum concentration profiles of Norelgestromin (NGMN) and Ethinylestradiol (EE) released from the contraceptive patch Ortho Evra®.