Published in

Beilstein-Institut, Beilstein Journal of Organic Chemistry, (4), 2008

DOI: 10.3762/bjoc.4.45

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One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

In this work an efficient one-pot synthesis of substituted pyrroles 7a–n is described, which involves the in situ formation of dihydrofurans ethyl 5-butoxy-2-methyl-4,5-dihydrofuran-3-carboxylate (4), 1-(5-butoxy-2-methyl-4,5-dihydrofuran-3-yl)ethanone (5) and 5-butoxy-4,5-dihydrofuran-3-carbaldehyde (6) followed by reaction with primary amines.