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Genome-wide association study identifies multiple loci associated with bladder cancer risk.
Journal article published in 2013 by
Jonine D. Figueroa,
Figueroa Jd,
Yuanqing Ye,
Afshan Siddiq,
Montserrat Garcia-Closas,
Nilanjan Chatterjee,
Ludmila Prokunina-Olsson,
Vk K. Cortessis 
,
Cortessis Vk,
Charles Kooperberg,
Olivier Cussenot,
Simone Benhamou,
Jennifer Prescott,
Stefano Porru,
Dinney Cp
and other authors.
,
Cortessis Vk,
Charles Kooperberg,
Olivier Cussenot,
Simone Benhamou,
Jennifer Prescott,
Stefano Porru,
Dinney Cp
and other authors.
Abstract
Candidate gene and genome-wide association studies (GWAS) have identified 11 independent susceptibility loci associated with bladder cancer risk. To discover additional risk variants, we conducted a new GWAS of 2422 bladder cancer cases and 5751 controls, followed by a meta-analysis with two independently published bladder cancer GWAS, resulting in a combined analysis of 6911 cases and 11 814 controls of European descent. TaqMan genotyping of 13 promising single nucleotide polymorphisms with P