Dissemin is shutting down on January 1st, 2025

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Wiley, Annals of Human Genetics, 4(75), p. 456-467, 2011

DOI: 10.1111/j.1469-1809.2011.00654.x

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Genetic Variants Associated with von Willebrand Factor Levels in Healthy Men and Women Identified Using the HumanCVD BeadChip

Journal article published in 2011 by Delilah Zabaneh, Tom R. Gaunt, Meena Kumari, Fotios Drenos ORCID, Sonia Shah, Diane Berry, Chris Power, Elina Hypponen ORCID, Tina Shah, Jutta Palmen, Jacky Pallas, Philippa J. Talmud, Juan Pablo Casas, Reecha Sofat, Gordon Lowe and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We have used the gene-centric Illumina HumanCVD BeadChip to identify common genetic determinants of Von Willebrand factor (vWF) levels in healthy men and women.The Whitehall II (WHII) study (n = 5592) and the British Women's Heart and Health Study (BWHHS) (n = 3445) were genotyped using the HumanCVD BeadChip. Replication was conducted in the British Regional Heart Study (n = 3897) and 1958 Birth Cohort (n = 5048).We identified 48 single nucleotide polymorphisms (SNPs) in four genes/regions associated with vWF at P