American Society of Hematology, Blood, 11(127), p. 1426-1437, 2016
DOI: 10.1182/blood-2015-10-673749
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Key Points A new Gata2 reporter indicates that all HSCs express Gata2 and corroborates findings that Gata2 is not required for generation of all HPCs. Isolatable non–Gata2-expressing HPCs show less potency and a distinct genetic program, thus having implications for reprogramming strategies.