Cell Press, Molecular Cell, 5(41), p. 495-496, 2011
DOI: 10.1016/j.molcel.2011.02.014
Full text: Unavailable
In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer-prone.