Published in
Bentham Open, Open Respiratory Medicine Journal, 1(3), p. 94-99
DOI: 10.2174/1874306400903010094
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- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Effectiveness of Rituximab in Severe Wegener’s Granulomatosis: Report of Two Cases and Review of the Literature
Journal article published in 2009 by
Joaquim Oristrell 
,
Guillermina Bejarano,
Rosa Jordana,
Manuel Monteagudo,
Begoña Marí,
Arnau Casanovas,
Carles Tolosa
,
Guillermina Bejarano,
Rosa Jordana,
Manuel Monteagudo,
Begoña Marí,
Arnau Casanovas,
Carles Tolosa
This paper is made freely available by the publisher.
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Abstract
We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener’s granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented.