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Springer, European Radiology, 11(22), p. 2415-2423, 2012

DOI: 10.1007/s00330-012-2503-5

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Computed tomography coronary angiography accuracy in women and men at low to intermediate risk of coronary artery disease

Journal article published in 2012 by Anoeshka S. Dharampal, Dharampal As, Stella L. Papadopoulou ORCID, Annick C. Weustink, Papadopoulou Sl, Alexia Rossi, Weustink Ac, Nico R. A. Mollet, Mollet Nr, W. Bob Meijboom, Pim J. de Feijter, W. Bob Meijboom, Meijboom Wb, Lisan A. Neefjes, Neefjes La and other authors.
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Abstract

OBJECTIVES: To investigate the diagnostic accuracy of CT coronary angiography (CTCA) in women at low to intermediate pre-test probability of coronary artery disease (CAD) compared with men. METHODS: In this retrospective study we included symptomatic patients with low to intermediate risk who underwent both invasive coronary angiography and CTCA. Exclusion criteria were previous revascularisation or myocardial infarction. The pre-test probability of CAD was estimated using the Duke risk score. Thresholds of less than 30 % and 30-90 % were used for determining low and intermediate risk, respectively. The diagnostic accuracy of CTCA in detecting obstructive CAD (≥50 % lumen diameter narrowing) was calculated on patient level. P