Published in
Elsevier, NeuroImage: Clinical, (5), p. 62-68, 2014
DOI: 10.1016/j.nicl.2014.05.015
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Larger amygdala volume in first-degree relatives of patients with major depression
Journal article published in 2014 by
Nina Romanczuk-Seiferth 
,
Lydia Pöhland,
Sebastian Mohnke,
Maria Garbusow,
Susanne Erk ,
Leila Haddad,
Oliver Grimm,
Heike Tost,
Andreas Meyer-Lindenberg ,
Henrik Walter,
Torsten Wüstenberg ,
Andreas Heinz
,
Lydia Pöhland,
Sebastian Mohnke,
Maria Garbusow,
Susanne Erk ,
Leila Haddad,
Oliver Grimm,
Heike Tost,
Andreas Meyer-Lindenberg ,
Henrik Walter,
Torsten Wüstenberg ,
Andreas Heinz
This paper is made freely available by the publisher.
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Abstract
•Brain structure of high-risk subjects might indicate intermediate phenotypes of MDD•63 first-degree relatives of MDD patients/ 63 healthy controls were studied•Local gray matter volumes were analyzed via VBM•Analysis revealed larger volume in bilateral amygdalae in relatives of MDD patients•Brain volume differences point to a vulnerability mechanism in MDD etiology