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EDP Sciences, médecine/sciences, 3(29), p. 279-285, 2013

DOI: 10.1051/medsci/2013293014

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Quand l’urine cisaille les cellules rénales

Journal article published in 2013 by Julien Gonzalez, Marie Essig ORCID, Julie Klein, Cécile Caubet, Romain Dissard, Jean-Loup Bascands, Joost P. Schanstra ORCID, Bénédicte Buffin-Meyer
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This paper is available in a repository.

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Abstract

The role of fluid shear stress is well established in vascular pathophysiology. However, urinary shear stress now also appears as a key mechanism in the regulation of renal function. In addition, there is a growing body of evidence showing that modified urinary shear stress is involved in the development of nephropathies. Therefore we review here the state-of-the-art on the pathophysiological roles of urinary shear stress.