Published in

The Company of Biologists, Development, 3(138), p. 387-396, 2011

DOI: 10.1242/dev.048934

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Evolutionary crossroads in developmental biology: Dictyostelium discoideum

Journal article published in 2011 by Pauline Schaap ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Dictyostelium discoideum belongs to a group of multicellular life forms that can also exist for long periods as single cells. This ability to shift between uni- and multicellularity makes the group ideal for studying the genetic changes that occurred at the crossroads between uni- and multicellular life. In this Primer, I discuss the mechanisms that control multicellular development in Dictyostelium discoideum and reconstruct how some of these mechanisms evolved from a stress response in the unicellular ancestor.