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The deformation behavior of amorphous selenium near its glass transition temperature (31 °C) has been investigated by uniaxial compression and nanoindentation creep tests. Cylindrical specimens compressed at high temperatures and low strain rates deform stably into barrel-like shapes, while tests at low temperatures and high strain rates lead to fragmentation. These results agree well with stress exponent and kinetic activation parameters extracted from nanoindentation creep tests using a similarity analysis. The dependence of the deformation modes on temperature and strain rate can be understood as a consequence of material instability and strain localization in rate-dependent solids.