Published in
Wiley, Angewandte Chemie International Edition, 52(52), p. 14065-14069, 2013
Wiley, Angewandte Chemie, 52(125), p. 14315-14319, 2013
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- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Acetylcholinesterase-Catalyzed Hydrolysis Allows Ultrasensitive Detection of Pathogens with the Naked Eye**
Journal article published in 2013 by
Dingbin Liu,
Zhantong Wang,
Albert Jin 
,
Xinglu Huang,
Xiaolian Sun,
Fu Wang,
Qiang Yan,
Shengxiang Ge,
Ningshao Xia,
Gang Niu,
Gang Liu,
A. R. Hight Walker,
A. R. HightWalker,
Xiaoyuan Chen
,
Xinglu Huang,
Xiaolian Sun,
Fu Wang,
Qiang Yan,
Shengxiang Ge,
Ningshao Xia,
Gang Niu,
Gang Liu,
A. R. Hight Walker,
A. R. HightWalker,
Xiaoyuan Chen
This paper is available in a repository.
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Abstract
Seeing is believing: A rapid diagnostic platform for pathogen detection based on the acetylcholinesterase-catalyzed hydrolysis reaction has been developed. Owing to signal amplification strategies, the sensitivity of this assay is comparable to that of PCR. In addition, the readout of the assay is based on solution color change, which can be easily observed by the naked eye alone.