Habitual exercise plus dietary supplementation with milk fat globule membrane improves muscle function deficits via neuromuscular development in senescence-accelerated mice

Haramizu, Satoshi; Mori, Takuya; Yano, Michiko; Ota, Noriyasu; Hashizume, Kohjiro; Otsuka, Atsuko; Hase, Tadashi; Shimotoyodome, Akira

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Habitual exercise plus dietary supplementation with milk fat globule membrane improves muscle function deficits via neuromuscular development in senescence-accelerated mice

Journal article published in 2014 by Satoshi Haramizu, Takuya Mori, Michiko Yano, Noriyasu Ota, Kohjiro Hashizume, Atsuko Otsuka, Tadashi Hase, Akira Shimotoyodome

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Abstract

We examined the effects of habitual exercise plus nutritional intervention through consumption of milk fat globule membrane (MFGM), a milk component, on aging-related deficits in muscle mass and function in senescence-accelerated P1 mice. Combining wheel-running and MFGM (MFGMEx) intake significantly attenuated age-related declines in quadriceps muscle mass (control: 318 ± 6 mg; MFGMEx: 356 ± 9 mg; P