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American Association for the Advancement of Science, Science Translational Medicine, 5(1), 2009

DOI: 10.1126/scitranslmed.3000237

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Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Dysfunctional genotype combinations of polymorphic adenosine 5′-triphosphate–binding cassette transporter gene ABCG2/BCRP , which encodes a high-capacity urate secretion transporter in human gut and kidney, are major causes of gout.