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Public Library of Science, PLoS ONE, 8(7), p. e42563, 2012

DOI: 10.1371/journal.pone.0042563

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Rho GTPase Expression in Human Myeloid Cells

Journal article published in 2012 by Suzanne F. G. van Helden, Eloise C. Anthony, Rob Dee, Peter L. Hordijk ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Myeloid cells are critical for innate immunity and the initiation of adaptive immunity. Strict regulation of the adhesive and migratory behavior is essential for proper functioning of these cells. Rho GTPases are important regulators of adhesion and migration; however, it is unknown which Rho GTPases are expressed in different myeloid cells. Here, we use a qPCR-based approach to investigate Rho GTPase expression in myeloid cells.