Published in
Elsevier, Journal of Allergy and Clinical Immunology, 4(135), p. 998-1007.e6, 2015
DOI: 10.1016/j.jaci.2014.08.030
Links
- ORCID
- Elsevier
- ORCID
- [discovery.ucl.ac.uk]
- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
Tools
An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex.
Journal article published in 2014 by
Sven Kracker,
Michela Di Virgilio,
Jeremy Schwartzentruber 
,
Cyrille Cuenin,
Monique Forveille,
Mc Deau ,
Km McBride,
Jacek Majewski,
Anna Gazumyan,
Suranjith Seneviratne,
Bodo Grimbacher,
Necil Kutukculer,
Zdenko Herceg,
Marina Cavazzana,
Nada Jabado
and other authors.
,
Cyrille Cuenin,
Monique Forveille,
Mc Deau ,
Km McBride,
Jacek Majewski,
Anna Gazumyan,
Suranjith Seneviratne,
Bodo Grimbacher,
Necil Kutukculer,
Zdenko Herceg,
Marina Cavazzana,
Nada Jabado
and other authors.
This paper is available in a repository.
Full text: Download
Published version:
archiving forbidden
Data provided by 
Abstract
Immunoglobulin class-switch recombination defects (CSR-D) are rare primary immunodeficiencies characterized by impaired production of switched immunoglobulin isotypes and normal or elevated IgM levels. They are caused by impaired T:B cooperation or intrinsic B cell defects. However, many immunoglobulin CSR-Ds are still undefined at the molecular level.