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BMJ Publishing Group, BMJ, jun04 2(348), p. g3510-g3510

DOI: 10.1136/bmj.g3510

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Benefits and harms in clinical trials of duloxetine for treatment of major depressive disorder: comparison of clinical study reports, trial registries, and publications

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Objective To determine, using research on duloxetine for major depressive disorder as an example, if there are inconsistencies between protocols, clinical study reports, and main publicly available sources (journal articles and trial registries), and within clinical study reports themselves, with respect to benefits and major harms.